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1

Oscillatory control of insulin secretion

Anders Tengholm, Erik Gylfe

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 1.17 MB

english, 2009

2

[Vitamins & Hormones] Insulin and IGFs Volume 80 || Chapter 11 Spatio‐Temporal Dynamics of Phosphatidylinositol‐3,4,5‐Trisphosphate Signalling

Tengholm, Anders

Year:

2009

Language:

english

File:

PDF, 525 KB

english, 2009

3

The endoplasmic reticulum is a glucose-modulated high-affinity sink for Ca2+ in mouse pancreatic β-cells

Anders Tengholm, Bo Hellman, Erik Gylfe

Journal:

The Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 207 KB

english, 2001

4

Tensin2 reduces intracellular phosphatidylinositol 3,4,5-trisphosphate levels at the plasma membrane

Sassan Hafizi, Anna Gustafsson, Cecilia Oslakovic, Olof Idevall-Hagren, Anders Tengholm, Olivier Sperandio, Bruno O. Villoutreix, Björn Dahlbäck

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 646 KB

english, 2010

5

Ca 2+ and cAMP Signaling in Human Embryonic Stem Cell–Derived Dopamine Neurons

Malmersjö, Seth, Liste, Isabel, Dyachok, Oleg, Tengholm, Anders, Arenas, Ernest, Uhlén, Per

Journal:

Stem Cells and Development

Year:

2010

Language:

english

File:

PDF, 1.24 MB

english, 2010

6

Single Cell Imaging of PI3K Activity and Glucose Transporter Insertion Into the Plasma Membrane by Dual Color Evanescent Wave Microscopy

Tengholm, A., Teruel, M. N., Meyer, T.

Journal:

Year:

2003

Language:

english

File:

PDF, 1.71 MB

english, 2003

7

Role of phosphodiesterases in the shaping of sub-plasma-membrane cAMP oscillations and pulsatile insulin secretion

Tian, G., Sagetorp, J., Xu, Y., Shuai, H., Degerman, E., Tengholm, A.

Journal:

Journal of Cell Science

Year:

2012

Language:

english

File:

PDF, 984 KB

english, 2012

8

Autocrine Signaling Underlies Fast Repetitive Plasma Membrane Translocation of Conventional and Novel Protein Kinase C Isoforms in β-cells

Wuttke, Anne, Yu, Qian, Tengholm, Anders

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 1.57 MB

english, 2016

9

ZBED6 negatively regulates insulin production, neuronal differentiation, and cell aggregation in MIN6 cells

Wang, Xuan, Jiang, Lin, Wallerman, Ola, Younis, Shady, Yu, Qian, Klaesson, Axel, Tengholm, Anders, Welsh, Nils, Andersson, Leif

Journal:

The FASEB Journal

Year:

2018

Language:

english

File:

PDF, 1.93 MB

english, 2018

10

Cyclic AMP: swing that message!

Journal:

Cellular and Molecular Life Sciences

Year:

2007

Language:

english

File:

PDF, 149 KB

english, 2007

11

The role of plasma membrane K+ and Ca2+ permeabilities for glucose induction of slow Ca2+ oscillations in pancreatic β-cells

Michael Eberhardson, Anders Tengholm, Eva Grapengiesser

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1996

Language:

english

File:

PDF, 497 KB

english, 1996

12

Anchored phosphatases modulate glucose homeostasis

Hinke, Simon A, Navedo, Manuel F, Ulman, Allison, Whiting, Jennifer L, Nygren, Patrick J, Tian, Geng, Jimenez-Caliani, Antonio J, Langeberg, Lorene K, Cirulli, Vincenzo, Tengholm, Anders, Dell‧Acqua,

Journal:

The EMBO Journal

Year:

2012

Language:

english

File:

PDF, 1.45 MB

english, 2012

13

Fluorescent protein vectors for pancreatic islet cell identification in live-cell imaging

Shuai, Hongyan, Xu, Yunjian, Yu, Qian, Gylfe, Erik, Tengholm, Anders

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2016

Language:

english

File:

PDF, 2.44 MB

english, 2016

14

Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung endothelial cells

Guangxiang Zang, Gustaf Christoffersson, Geng Tian, Mohammad Harun-Or-Rashid, Evelina Vågesjö, Mia Phillipson, Sebastian Barg, Anders Tengholm, Michael Welsh

Journal:

Cellular Signalling

Year:

2013

Language:

english

File:

PDF, 1.15 MB

english, 2013

15

Oscillations of Phospholipase C Activity Triggered by Depolarization and Ca2+ Influx in Insulin-secreting Cells

Thore, S., Dyachok, O., Tengholm, A.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 685 KB

english, 2004

16

Glucose controls glucagon secretion by directly modulating cAMP in alpha cells

Yu, Qian, Shuai, Hongyan, Ahooghalandari, Parvin, Gylfe, Erik, Tengholm, Anders

Journal:

Year:

2019

File:

PDF, 1.52 MB

2019

17

PI3-kinase p110α mediates β1 integrin-induced Akt activation and membrane protrusion during cell attachment and initial spreading

Kathrin S. Zeller, Olof Idevall-Hagren, Anne Stefansson, Teet Velling, Shaun P. Jackson, Julian Downward, Anders Tengholm, Staffan Johansson

Journal:

Cellular Signalling

Year:

2010

Language:

english

File:

PDF, 1.35 MB

english, 2010

18

Glucose Regulation of Free Ca2+ in the Endoplasmic Reticulum of Mouse Pancreatic Beta Cells

Tengholm, A., Hellman, B., Gylfe, E.

Journal:

Journal of Biological Chemistry

Year:

1999

Language:

english

File:

PDF, 788 KB

english, 1999

19

Distinct plasma-membrane PtdIns(4)P and PtdIns(4,5)P2 dynamics in secretagogue-stimulated -cells

Wuttke, A., Sagetorp, J., Tengholm, A.

Journal:

Journal of Cell Science

Year:

2010

Language:

english

File:

PDF, 2.03 MB

english, 2010

20

Glucose-Induced Cyclic AMP Oscillations Regulate Pulsatile Insulin Secretion

Oleg Dyachok, Olof Idevall-Hagren, Jenny Sågetorp, Geng Tian, Anne Wuttke, Cécile Arrieumerlou, Göran Akusjärvi, Erik Gylfe, Anders Tengholm

Journal:

Cell Metabolism

Year:

2008

Language:

english

File:

PDF, 1.44 MB

english, 2008

21

Functional differences between aggregated and dispersed insulin-producing cells

A. Chowdhury, O. Dyachok, A. Tengholm, S. Sandler, P. Bergsten

Journal:

Year:

2013

Language:

english

File:

PDF, 401 KB

english, 2013

22

Glucose- and Hormone-Induced cAMP Oscillations in - and -Cells Within Intact Pancreatic Islets

Tian, G., Sandler, S., Gylfe, E., Tengholm, A.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.39 MB

english, 2011

23

P2Y1 receptor-dependent diacylglycerol signaling microdomains in cells promote insulin secretion

Wuttke, A., Idevall-Hagren, O., Tengholm, A.

Journal:

The FASEB Journal

Year:

2013

Language:

english

File:

PDF, 1.35 MB

english, 2013

24

Signaling Underlying Pulsatile Insulin Secretion

Gylfe, Erik, Ahmed, Meftun, Bergsten, Peter, Dansk, Heléne, Dyachok, Oleg, Eberhardson, Michael, Grapengiesser, Eva, Hellman, Bo, Lin, Jian-Man, Lin, Jian-Man, Tengholm, Anders, Vieira, Elaine, Wester

Journal:

Upsala Journal of Medical Sciences

Year:

2000

Language:

english

File:

PDF, 1.29 MB

english, 2000

25

Î³-Hydroxybutyrate does not mediate glucose inhibition of glucagon secretion

Yu, Qian, Lai, Bao Khanh, Ahooghalandari, Parvin, Helander, Anders, Gylfe, Erik, Gilon, Patrick, Tengholm, Anders

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 392 KB

2020

26

Rapid Turnover of Phosphatidylinositol-4,5-Bisphosphate in Insulin-Secreting Cells Mediated by Ca2+ and the ATP-to-ADP Ratio

Thore, S., Wuttke, A., Tengholm, A.

Journal:

Year:

2007

Language:

english

File:

PDF, 422 KB

english, 2007

27

Cyclic AMP links glucose stimulation to somatostatin secretion in Î´-cells

Tengholm, Anders

Journal:

The Journal of General Physiology

Year:

2019

File:

PDF, 684 KB

2019

28

Imatinib mesilate-induced phosphatidylinositol 3-kinase signalling and improved survival in insulin-producing cells: role of Src homology 2-containing inositol 5′-phosphatase interaction with c-Abl

Mokhtari, D., Al-Amin, A., Turpaev, K., Li, T., Idevall-Hagren, O., Li, J., Wuttke, A., Fred, R. G., Ravassard, P., Scharfmann, R., Tengholm, A., Welsh, N.

Journal:

Year:

2013

Language:

english

File:

PDF, 616 KB

english, 2013

29

In Situ Characterization of Nonmitochondrial Ca2+ Stores in Individual Pancreatic -Cells

Tengholm, A., Hagman, C., Gylfe, E., Hellman, B.

Journal:

Year:

1998

Language:

english

File:

PDF, 1.35 MB

english, 1998

30

Spatial Control of Epac2 Activity by cAMP and Ca2+-Mediated Activation of Ras in Pancreatic Cells

Idevall-Hagren, O., Jakobsson, I., Xu, Y., Tengholm, A.

Journal:

Science Signaling

Year:

2013

Language:

english

File:

PDF, 688 KB

english, 2013

31

Oscillations of sub-membrane ATP in glucose-stimulated beta cells depend on negative feedback from Ca2+

J. Li, H. Y. Shuai, E. Gylfe, A. Tengholm

Journal:

Year:

2013

Language:

english

File:

PDF, 460 KB

english, 2013

32

Submembrane ATP and Ca2+ kinetics in -cells: unexpected signaling for glucagon secretion

Li, J., Yu, Q., Ahooghalandari, P., Gribble, F. M., Reimann, F., Tengholm, A., Gylfe, E.

Journal:

The FASEB Journal

Year:

2015

Language:

english

File:

PDF, 1.70 MB

english, 2015

33

Neuropeptide S inhibits gastrointestinal motility and increases mucosal permeability through nitric oxide

Wan Saudi, Wan Salman, Halim, Md. Abdul, Rudholm-Feldreich, Tobias, Gillberg, Linda, Rosenqvist, Evelina, Tengholm, Anders, Sundbom, Magnus, Karlbom, Urban, Näslund, Erik, Webb, Dominic-Luc, Sjöblom,

Journal:

AJP Gastrointestinal and Liver Physiology

Year:

2015

Language:

english

File:

PDF, 2.77 MB

english, 2015

34

Oscillations of cyclic AMP in hormone-stimulated insulin-secreting β-cells

Dyachok, Oleg, Isakov, Yegor, Sågetorp, Jenny, Tengholm, Anders

Journal:

Year:

2006

Language:

english

File:

PDF, 346 KB

english, 2006

35

Purinergic P2Y1receptors take centre stage in autocrine stimulation of human beta cells

Tengholm, Anders

Journal:

Year:

2014

Language:

english

File:

PDF, 166 KB

english, 2014

36

Oscillatory Signaling and Insulin Release in Human Pancreaticβ -Cells Exposed to Strontium 1

B. Hellman, E. Gylfe, P. Bergsten, E. Grapengiesser, A. Berts, Y. Liu, A. Tengholm, J. Westerlund

Year:

1997

Language:

english

File:

PDF, 308 KB

english, 1997

37

Capacitative Ca2+ Entry via Orai1 and Stromal Interacting Molecule 1 (STIM1) Regulates Adenylyl Cyclase Type 8

Martin, A. C. L., Willoughby, D., Ciruela, A., Ayling, L.-J., Pagano, M., Wachten, S., Tengholm, A., Cooper, D. M. F.

Journal:

Molecular Pharmacology

Year:

2009

Language:

english

File:

PDF, 845 KB

english, 2009

38

cAMP signalling in insulin and glucagon secretion

Tengholm, A., Gylfe, E.

Journal:

Diabetes, Obesity and Metabolism

Year:

2017

Language:

english

File:

PDF, 1.56 MB

english, 2017

39

cAMP Induces Stromal Interaction Molecule 1 (STIM1) Puncta but neither Orai1 Protein Clustering nor Store-operated Ca2+ Entry (SOCE) in Islet Cells

Tian, G., Tepikin, A. V., Tengholm, A., Gylfe, E.

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 1.74 MB

english, 2012

40

Metabolic regulation of calcium signaling in beta cells

Idevall-Hagren, Olof, Tengholm, Anders

Journal:

Seminars in Cell & Developmental Biology

Year:

2020

Language:

english

File:

PDF, 1.48 MB

english, 2020

41

Mobilization of Ca2+stores in individual pancreatic β -cells permeabilized or not with digitonin or α -toxin

A. Tengholm, B. Hellman, E. Gylfe

Journal:

Year:

2000

Language:

english

File:

PDF, 218 KB

english, 2000

42

In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis

Petrenko, Volodymyr, Gandasi, Nikhil R., Sage, Daniel, Tengholm, Anders, Barg, Sebastian, Dibner, Charna

Journal:

Proceedings of the National Academy of Sciences

Year:

2020

File:

PDF, 1.47 MB

2020

43

Glucose and Insulin Synergistically Activate Phosphatidylinositol 3-Kinase to Trigger Oscillations of Phosphatidylinositol 3,4,5-Trisphosphate in beta-Cells

Hagren, O. I., Tengholm, A.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 1.13 MB

english, 2006

44

Recruitment of Epac2A to Insulin Granule Docking Sites Regulates Priming for Exocytosis

Alenkvist, Ida, Gandasi, Nikhil R., Barg, Sebastian, Tengholm, Anders

Journal:

Year:

2017

Language:

english

File:

PDF, 1.97 MB

english, 2017

45

Fusion Pore Regulation by EPAC2/cAMP Controls Cargo Release during Insulin Exocytosis

Gucek, Alenka, Gandasi, Nikhil R., Omar-Hmeadi, Muhmmad, Bakke, Marit, Doskeland, Stein, Tengholm, Anders, Barg, Sebastian

Journal:

Biophysical Journal

Year:

2019

Language:

english

File:

PDF, 43 KB

english, 2019

46

A Membrane Permeable Prodrug of S223 for Selective Epac2 Activation in Living Cells

Xu, Yunjian, Schwede, Frank, Wienk, Hans, Tengholm, Anders, Rehmann, Holger

Journal:

Year:

2019

File:

PDF, 3.42 MB

2019

47

Paracrine control of Î±-cell glucagon exocytosis is compromised in human type-2 diabetes

Omar-Hmeadi, Muhmmad, Lund, Per-Eric, Gandasi, Nikhil R., Tengholm, Anders, Barg, Sebastian

Journal:

Nature Communications

Year:

2020

File:

PDF, 3.24 MB

2020

48

Origin of slow and fast oscillations of Ca2+ in mouse pancreatic islets

Yi-Jia Liu, Anders Tengholm, Eva Grapengiesser, Bo Hellman, Erik Gylfe

Journal:

The Journal of Physiology

Year:

1998

Language:

english

File:

PDF, 1.07 MB

english, 1998

49

siRNA Produced by Recombinant Dicer Mediates Efficient Gene Silencing in Islet Cells

ROBERT HÄGERKVIST, DARIUSH MOKHTARI, JASON W. MYERS, ANDERS TENGHOLM, NILS WELSH

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 5.43 MB

english, 2005

50

Corrigendum to “PI3-kinase p110α mediates β1 integrin-induced Akt activation and membrane protrusion during cell attachment and initial spreading” [Cell. Signal. 22 (2010) 1838–1848]

Kathrin S. Zeller, Olof Idevall-Hagren, Anne Stefansson, Teet Velling, Shaun P. Jackson, Julian Downward, Anders Tengholm, Staffan Johansson

Journal:

Cellular Signalling

Year:

2012

Language:

english

File:

PDF, 207 KB

english, 2012

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